José Pereira Leal

Writing

Writing is not separate from the work. It is where experience becomes argument, where assumptions are tested, and where possible futures can be examined before they become commitments.

Books

Nonfiction and fiction.

Nonfiction

I write nonfiction to think through problems that are too large and too consequential for a strategy document. Both books emerge from the same three decades of building at the science-clinic interface: one looks back at what it takes to found a diagnostics company, the other looks forward at what it will take to build an entire sector.

Fiction

I write fiction to explore ideas that sit just beyond the reach of science. My professional life is shaped by evidence, data and the disciplines of precision medicine, yet many of the questions that interest me most, about transformation, belief, consequence and possibility, cannot be answered in a laboratory or an ecosystem strategy document. Stories allow me to examine the spaces where technology meets human uncertainty, where knowledge shifts faster than culture or people adapt, and where ambition defies our ability to predict impact.

Fiction gives me the freedom to test the boundaries of what we understand, to imagine how people and societies respond when confronted with the unfamiliar or the inevitable, and to trace the moral and emotional contours that lie beneath scientific progress. It is a way of thinking in another mode: speculative rather than analytical, but driven by the same curiosity about how the future is built, and what it may cost.

I have always loved reading, and in writing I stumbled on a similar but more visceral form of discovery. Characters acquire a life of their own; they make choices you did not expect and take the story in directions you had not planned. It feels like reading from the inside, and it is that sense of revelation, rather than control, that keeps me returning to fiction.

Precision Diagnostics: A Founder's Journey cover

Nonfiction · Published

Precision Diagnostics: A Founder's Journey

Why diagnostics, not drugs, are the future of medicine

A personal and professional account of what it takes to build diagnostics at the frontiers of medicine. Drawing on nearly thirty years across research, entrepreneurship, and clinical translation, this book offers an insider's perspective on turning cutting-edge science into tools that change patient care.

The Import Condition cover

Nonfiction · Current project

The Import Condition

Diagnostics, sovereignty and the Gulf’s industrial moment

The Gulf's most consequential health infrastructure challenge is not clinical; it is industrial. This book makes the case for why diagnostic sovereignty matters, what supply chain dependency actually costs, and how the GCC's current strategic moment creates both the need and the conditions for building something durable.

A Madness of the Moon cover

Fiction · Published as J.P. Leal

A Madness of the Moon

A novel of loss, identity and the courage to begin again

Dylan Blake came to Cape Cod to hide. He wanted only to grieve in peace. Then a poetry reading changed everything. In the village of Nobska Hole, where artists have always found refuge, science meets superstition, reason collides with legacy, and one man's search for truth becomes a journey toward renewal.

The Custodian of Murjan cover

Fiction · Work in progress as J.P. Leal

The Custodian of Murjan

Work in progress · Expected publication by end of 2026

What would you do if someone offered you the chance to build something truly large, but far from everything you know? What would you do if that person died and left you as custodian of his entire life and dreams? What would you do if everything familiar is gone, and you are now faced with a world whose rules, codes and silences are completely alien to you? What follows is a story about belonging: what it costs, what it requires, and what it means to arrive somewhere so completely that you can no longer remember the person who left.

White papers & frameworks

Formal statements of work and method.

White paper · Version 1.0 · 2026

Diagnostics Readiness Levels (DRL)

A Multi-Dimensional Framework for Diagnostic and Biomarker Development

A working proposal grounded in practitioner experience and offered as a structured tool for development teams, investors and evaluators, and as a basis for community refinement.

White paper · In preparation

Zullya white paper

A stable account of the method and its evidential limits

A concise account of the problem, method, theoretical rationale, intended use and current evidential limits. The first stable edition is intended to receive a persistent citation record.

Essays & commentary

Ideas before they become projects.

Shorter work organised around three evolving territories: diagnostics sovereignty, precision diagnostics, and systems and futures.

02

Diagnostics sovereignty · 24 June 2026

Small Is Better

Why the Gulf’s diagnostics sovereignty moment demands the right industrial architecture rather than another oversized promise.

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04

Diagnostics sovereignty · 18 May 2026

The Plasticware Paradox

How a region that exports the feedstock for molecular medicine still imports nearly every finished component required to practise it.

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Science

Scientific publications

Scientific writing has been a continuous part of my professional life. My peer-reviewed publications span genomics and bioinformatics, systems biology, cancer genomics, biomarker discovery, precision diagnostics and translational medicine.

View the scientific record